From December 26 to 28, 2025, the 2nd IEEE International Conference on Software Systems and Information Processing (IEEE ICSSIP 2025) was conducted in a combined online and offline format, which was held in Chengdu. Co-hosted by the School of Information and Communication Engineering, University of Electronic Science and Technology of China (UESTC) and the Institute of Electrical and Electronics Engineers (IEEE), the conference gathered experts, scholars, university teachers and students from multiple countries and regions. They jointly discussed the latest advancements and application prospects in various cutting-edge fields such as computer software systems, wireless communications, and signal processing.